Nutrition Health Review

Summer 2017

Nutrition Health Review provides consumers updates on the latest medical research, news, trends, and products in nutrition and healthy living.

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Nutrition Health Review 8 Regular exercise is One of the Keys to healthy skin by nhR staff W e all have heard of the many benefits that regular exercise has on cardiovascular health, including body weight management, reduction in blood pressure, reduction in bad (LDL and total) cholesterol, increase in good (HDL) cholesterol, and increase in insulin sensitivity. 1 But did you know that regular exercise is good for your skin as well? A group of researchers from McMaster University in Ontario, Canada, found that after age 40, the men and women who exercised frequently had markedly thinner, healthier stratum corneums (outer layer of the skin) and thicker dermis layers (the living tissue below the epidermis) in their skin. Their skin was much closer in composition to that of the 20- and 30-year-olds than to that of others of their age, even if they were past age 65. How exercise changes skin composition is not completely clear, but in a separate portion of the study, the researchers checked for alterations in the levels of certain substances created by working muscles. Called myokines, these substances are known to enter the bloodstream and jump-start changes in cells far from the muscles themselves. In this case, the scientists found greatly augmented levels of a myokine called IL-15 in the skin samples of volunteers after exercise. Their skin samples contained almost 50-percent more IL-15 after they had been exercising than at the start of the study. The researchers suspect that additional myokines and other substances are involved in the skin changes related to exercise, making it unlikely that any IL-15 pill, salve, or injection will ever replicate the skin benefits of a workout. SOURCES: 1) Myers J. Exercise and cardiovascular health. Circulation. 2003;107:e2–e5; 2) Reynolds G. Younger skin through exercise. April 16, 2014. The New York Times site. https://well.blogs.nytimes.com/2014/04/16/younger-skin-through-exercise/?mcubz=0. Accessed September 1, 2017; 3) Crane JD, et al. Exercise-stimulated interleukin-15 is controlled by AMPK and regulates skin metabolism and aging. Aging Cell. 2015 Aug;14(4):625-34. Epub 2015 Apr 22. NHR 3-d Bioprinter to Print human skin by nhR staff S cientists from the Universidad Carlos III de Madrid Center for Energy, Environmental, and Technological Research, Hospital General Universitario Gregorio Marañón, in collaboration with the firm BioDan Group, have presented a prototype for a 3D bioprinter that can create totally functional human skin. This skin is adequate for transplanting to patients, for use in research, or the testing of cosmetic, chemical, and pharmaceutical products. SOURCE: Universidad Carlos III de Madrid - Oficina de Información Científica. 3-D bioprinter to print human skin. ScienceDaily site. 23 January 2017. www.sciencedaily.com/releases/2017/01/ 170123090630.htm. Accessed September 1, 2017. NHR likely "wrong and may even promote cutaneous malignant melanoma (CMM)." 9 Here's an explanation from a natural health site for why this may be: "First of all, you need a shorter exposure time [to produce vitamin D] because the UVB is more intense." (Remember, vitamin D is supposed to protect us from too much sun.) "...when the sun goes down towards the horizon, the UVB is filtered out much more than the UVA. And it turns out that the long wave of ultraviolet called UVA...is highly correlated with melanoma—where the UVB is the one that produces the vitamin D..." 10 So UVB is highest at noon, which is used to produce vitamin D, and thus vitamin D production is highest at noon..and vitamin D protects us from the sun. Make sense? Conclusion I think it's fair for us to conclude that moderate, consistent sun exposure might be healthier than strict avoidance or chronic, daily exposure. But before you start singing the Bain de Soleil jingle, consider this: What's "moderate" for you might be very different than what's "moderate" for me, because things like skin type and geographical location can impact your skin's tolerance and the sun's strength, so use common sense. It also seems prudent to use sunscreen with an SPF of 30 or greater if you are going to be exposed to direct sunlight for longer than 10 minutes. SOURCES: 1) Skin Cancer Foundation site. History. http://www.skincancer.org/ about-us/history-of-the-foundation. Accessed September 1, 2017; 2) Sunscreen FAQs. American Academy of Dermatology site. https://www.aad.org/media/ stats/ prevention- and-care/sunscreen-faqs. Accessed September 1, 2017; 3). van der Rhee, et al. Regular sun exposure benefits health. Medical Hypotheses. 2016;97:34–37;) 4) Razzaque, et al. Sunlight exposure: Do health benefits outweigh harm? J Steroid Biochemis Molecul Biol. 16 September 2016 E-pub ahead of print; 5) Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr. 2004;80(6 Suppl):1678S–1688S. 6) Nelemans PJ, et al. Effect of intermittent exposure to sunlight on melanoma risk among indoor workers and sun- sensitive individuals. Environ Health Perspect. 1993;101(3):252–255; 7) Kennedy C, et al. The influence of painful sunburns and lifetime sun exposure on the risk of actinic keratoses, seborrheic warts, melanocytic nevi, atypical nevi, and skin cancer. J Invest Dermatol. 2003;120(6): 1087–1093; 8. Holly EA, et al. Cutaneous melanoma in women. I. Exposure to sunlight, ability to tan, and other risk factors related to ultraviolet light. Am J Epidemiol. 1995;141(10):923–933; 9) Dixon KM, et al. 1α,25(OH)₂-vitamin D and a nongenomic vitamin D analogue inhibit ultraviolet radiation-induced skin carcinogenesis. Cancer Prev Res (Phila). 2011;4(9):1485-94; 10) Moan J, et al. At what time should one go out in the sun? Adv Exp Med Biol. 2008;624:86–88. NHR h ealthy exposure to sunlight, con't from p7

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